ea0004p99 | Bone | SFE2002
White H
, Ahmad A
, Chandran S
, Clewes A
, Thomas J
, Durham B
, Vora J
, Fraser W
BACKGROUND: Adult growth hormone deficiency (AGHD) is associated with osteoporosis. Growth Hormone replacement (GHR) results in increased bone mineral density (BMD), with greater benefit derived in men. PTH plays an important role in bone metabolism and reports suggest that bone and renal insensitivity to PTH may contribute to changes in bone turnover in AGHD.OBJECTIVES: To determine the gender difference in PTH, phosphocalcium metabolism and bone turnov...